2. Metabolic Enzyme/Protease
  3. Isocitrate Dehydrogenase (IDH)
  4. 1816272-20-4

1816272-20-4

(S,S)-GSK321 Chemical Structure

1816272-20-4

Chemical Structure

  • (S,S)-GSK321
  • CAS No: 1816272-20-4
    Formula: C28H28FN5O3
    Molecular Weight: 501.55
  • IUPAC Name: (S)-1-(4-fluorobenzyl)-N-(3-((S)-1-hydroxyethyl)phenyl)-7-methyl-5-(1H-pyrrole-2-carbonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide
  • InChIKey: IVFDDVKCCBDPQZ-ROUUACIJSA-N
  • SMILES: C[C@H](O)C1=CC=CC(NC(C2=NN(C3=C2CN(C[C@@H]3C)C(C4=CC=CN4)=O)CC5=CC=C(C=C5)F)=O)=C1

Biological Activity: (S,S)-GSK321 is a (S,S)-enantiomer of GSK321[1].

Cat. No. Product Name Purity Description
HY-128888A (S,S)-GSK321 99.78% (S,S)-GSK321 is a (S,S)-enantiomer of GSK321.

References

[1]. Okoye-Okafor UC, et al. New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat Chem Biol. 2015 Nov;11(11):878-86. [Content Brief]

Keywords:

(S,S)-GSK321