2. Protein Tyrosine Kinase/RTK Epigenetics Cell Cycle/DNA Damage
  3. FLT3 HDAC
  4. 3458-22-8

3458-22-8

Yoshi-864 Chemical Structure

3458-22-8

Chemical Structure

  • Yoshi-864
  • Synonym(s): NSC-102627
  • CAS No: 3458-22-8
    Formula: C8H20ClNO6S2
    Molecular Weight: 325.83
  • IUPAC Name: azanediylbis(propane-3,1-diyl) dimethanesulfonate hydrochloride
  • InChIKey: YWCASUPWYFFUHE-UHFFFAOYSA-N
  • SMILES: CS(=O)(OCCCNCCCOS(C)(=O)=O)=O.[H]Cl

Biological Activity: Yoshi-864 (NSC-102627) is an alkylsulfonate DNA crosslinker with anticancer activity. Yoshi-864 extends markedly the survival times of mice bearing L1210 leukemia or Ehrlich ascites carcinoma. Yoshi-864 also has a persistent reduction in ability to synthesize DNA in tumor cells from mice bearing the Ehrlich tumor[1].

Cat. No. Product Name Purity Description
HY-129762 Yoshi-864 Yoshi-864 (NSC-102627) is an alkylsulfonate DNA crosslinker with anticancer activity. Yoshi-864 extends markedly the survival times of mice bearing L1210 leukemia or Ehrlich ascites carcinoma. Yoshi-864 also has a persistent reduction in ability to synthesize DNA in tumor cells from mice bearing the Ehrlich tumor.

References

[1]. Gale GR, et al. Comparative effects of Yoshi-864 and busulfan on certain transplantable murine tumors. Proc Soc Exp Biol Med. 1975 May;149(1):98-101. [Content Brief]

Keywords:

Yoshi-864