2. GPCR/G Protein
  3. Angiotensin Receptor
  4. 187683-79-0

187683-79-0

EMD-66684 potassium salt Chemical Structure

187683-79-0

Chemical Structure

  • EMD-66684 potassium salt
  • CAS No: 187683-79-0
    Formula: C28H29KN8O2
    Molecular Weight: 548.68
  • IUPAC Name: 2-(3-((2'-(1l2-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-oxo-3,4-dihydro-5H-imidazo[4,5-c]pyridin-5-yl)-N,N-dimethylacetamide, potassium salt
  • InChIKey: GDGHMGYJEWPZCD-UHFFFAOYSA-N
  • SMILES: O=C1C2=C(C=CN1CC(N(C)C)=O)N=C(CCCC)N2CC3=CC=C(C4=C(C5=NN=N[N-]5)C=CC=C4)C=C3.[K+]

Biological Activity: EMD-66684 potassium salt is a non-peptide angiotensin II receptor antagonist that demonstrates significant antihypertensive effects in spontaneously hypertensive rats. EMD-66684 potassium salt exhibits nanomolar affinity for angiotensin II receptors, comparable to losartan in potency. EMD-66684 potassium salt shows increased activity when modified with acetamides, leading to superior blood pressure reduction.

Cat. No. Product Name Purity Description
HY-103247B EMD-66684 potassium salt EMD-66684 potassium salt is a non-peptide angiotensin II receptor antagonist that demonstrates significant antihypertensive effects in spontaneously hypertensive rats. EMD-66684 potassium salt exhibits nanomolar affinity for angiotensin II receptors, comparable to losartan in potency. EMD-66684 potassium salt shows increased activity when modified with acetamides, leading to superior blood pressure reduction.

Keywords:

EMD-66684 potassium salt