2. Others
  3. Fluorescent Dye
  4. 2411681-92-8

2411681-92-8

Desthiobiotin-PEG3-NHS ester Chemical Structure

2411681-92-8

Chemical Structure

  • Desthiobiotin-PEG3-NHS ester
  • CAS No: 2411681-92-8
    Formula: C23H38N4O9
    Molecular Weight: 514.57
  • IUPAC Name: 2,5-dioxopyrrolidin-1-yl 19-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)-14-oxo-4,7,10-trioxa-13-azanonadecanoate
  • InChIKey: JWHMGEZINQQWSX-ZWKOTPCHSA-N
  • SMILES: O=C(N[C@H]1C)N[C@@H]1CCCCCC(NCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O)=O

Biological Activity: Desthiobiotin-PEG3-NHS ester is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015 M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin.

Cat. No. Product Name Purity Description
HY-D2759 Cyanine3B azide Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction. Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength. This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.

Keywords:

Desthiobiotin-PEG3-NHS ester