2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. 1941168-65-5

1941168-65-5

MC-Sq-Cit-PAB-Dolastatin10 Chemical Structure

1941168-65-5

Chemical Structure

  • MC-Sq-Cit-PAB-Dolastatin10
  • CAS No: 1941168-65-5
    Formula: C70H105N12O12S
    Molecular Weight: 1338.72
  • IUPAC Name: (S)-N-(4-((S)-2-(1-((5-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentyl)carbamoyl)cyclobutane-1-carboxamido)-5-ureidopentanamido)benzyl)-1-(((S)-1-(((3R,4S,5S)-3-methoxy-1-((S)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)p
  • InChIKey: QRUVDEDARGSTNP-OGGKWGLUSA-O
  • SMILES: C[N+]([C@H](C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C2=NC=CS2)CC3=CC=CC=C3)=O)CCC1)=O)C)=O)C(C)C)=O)C(C)C)(CC4=CC=C(NC([C@@H](NC(C5(C(NCCCCCN6C(C=CC6=O)=O)=O)CCC5)=O)CCCNC(N)=O)=O)C=C4)C

Biological Activity: MC-Sq-Cit-PAB-Dolastatin10 is a agent-linker conjugate for ADC with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.

Cat. No. Product Name Purity Description
HY-128894 MC-Sq-Cit-PAB-Dolastatin10 MC-Sq-Cit-PAB-Dolastatin10 is a agent-linker conjugate for ADC with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.

Keywords:

MC-Sq-Cit-PAB-Dolastatin10