2. Epigenetics
  3. Histone Methyltransferase
  4. 1612192-04-7

1612192-04-7

9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine Chemical Structure

1612192-04-7

Chemical Structure

  • 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine
  • CAS No: 1612192-04-7
    Formula: C10H12FN5O3
    Molecular Weight: 269.23
  • IUPAC Name: (2R,3S,4S,5R)-2-(2-amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
  • InChIKey: SARAHSXQPRQRAM-JXOAFFINSA-N
  • SMILES: OC[C@@H]1[C@@H](F)[C@@H](O)[C@H](N2C=NC3=C2N=C(N)N=C3)O1

Biological Activity: 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cat. No. Product Name Purity Description
HY-154643 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Keywords:

9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine