2. Epigenetics
  3. Epigenetic Reader Domain Histone Acetyltransferase
  4. 2018300-62-2

2018300-62-2

TPOP146 Chemical Structure

2018300-62-2

Chemical Structure

  • TPOP146
  • CAS No: 2018300-62-2
    Formula: C27H35N3O5
    Molecular Weight: 481.58
  • IUPAC Name: (S)-7-(3,5-dimethoxyphenyl)-N-(1-methylpiperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine-9-carboxamide
  • InChIKey: CUJLWYCUPPPASA-NRFANRHFSA-N
  • SMILES: COC1=CC(OC)=CC(C2=CC(C(N[C@H]3CCCN(C)C3)=O)=C(OCCN(C(CC)=O)C4)C4=C2)=C1

Biological Activity: TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor with Kd values of 134 nM and 5.02 μM for CBP and BRD4.

Cat. No. Product Name Purity Description
HY-100697 TPOP146 98.98% TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor with Kd values of 134 nM and 5.02 μM for CBP and BRD4.

Keywords:

TPOP146