2. Others
  3. Drug Intermediate
  4. 2235-97-4

2235-97-4

Dimethylamiloride hydrochloride Chemical Structure

2235-97-4

Chemical Structure

  • Dimethylamiloride hydrochloride
  • CAS No: 2235-97-4
    Formula: C8H13Cl2N7O
    Molecular Weight: 294.14
  • IUPAC Name: 3-amino-N-carbamimidoyl-6-chloro-5-(dimethylamino)pyrazine-2-carboxamide hydrochloride
  • InChIKey: IIUPTHVVXMBJMQ-UHFFFAOYSA-N
  • SMILES: O=C(C1=NC(Cl)=C(N(C)C)N=C1N)NC(N)=N.Cl

Biological Activity: Dimethylamiloride hydrochloride is a Na+/H+ exchanger NHE inhibitor with Ki values of 0.02, 0.25, and 14 μM for NHE1, NHE2, and NHE3, respectively. Dimethylamiloride hydrochloride can be used for pain research[1].

Cat. No. Product Name Purity Description
HY-132181 Dimethylamiloride hydrochloride Dimethylamiloride hydrochloride is a Na+/H+ exchanger NHE inhibitor with Ki values of 0.02, 0.25, and 14 μM for NHE1, NHE2, and NHE3, respectively. Dimethylamiloride hydrochloride can be used for pain research.

References

[1]. Masereel B, et al. An overview of inhibitors of Na(+)/H(+) exchanger. Eur J Med Chem. 2003 Jun;38(6):547-54. [Content Brief]

Keywords:

Dimethylamiloride hydrochloride