2. Others
  3. Fluorescent Dye
  4. 2488872-31-5

2488872-31-5

Carbonic anhydrase inhibitor 13 Chemical Structure

2488872-31-5

Chemical Structure

  • Carbonic anhydrase inhibitor 13
  • CAS No: 2488872-31-5
    Formula: C17H15N5O3S2
    Molecular Weight: 401.46
  • IUPAC Name: 4-(3-(3-methylbenzo[4,5]imidazo[2,1-b]thiazol-2-yl)ureido)benzenesulfonamide
  • InChIKey: YURIRWNDJSOTFB-UHFFFAOYSA-N
  • SMILES: O=S(C1=CC=C(NC(NC2=C(C)N3C4=CC=CC=C4N=C3S2)=O)C=C1)(N)=O

Biological Activity: Carbonic anhydrase inhibitor 13 (compound 7) is a potent carbonic anhydrase (CA) inhibitor, which features 3-methylthiazolo[3,2-a]benzimidazole moiety (as a tail) connected to the zinc anchoring benzenesulfonamide moiety via ureido linker[1].

Cat. No. Product Name Purity Description
HY-155482 NA-184 99.66% NA-184 is a selective calpain-2 inhibitor. NA-184 inhibits TBI-induced cell death with an EC50 of 0.13 mg/kg.

References

[1]. Alkhaldi AAM, et al. 3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies. Eur J Med Chem. 2020 Dec 1;207:1 [Content Brief]

Keywords:

Carbonic anhydrase inhibitor 13