1. Neuronal Signaling
  2. Beta-secretase
  3. 212571-56-7

212571-56-7

TAK-070 Free base Chemical Structure

212571-56-7

Chemical Structure

  • TAK-070 Free base
  • CAS No: 212571-56-7
    Formula: C27H31NO
    Molecular Weight: 385.54
  • IUPAC Name: (R)-2-(6-([1,1'-biphenyl]-4-ylmethoxy)-1,2,3,4-tetrahydronaphthalen-2-yl)-N,N-dimethylethan-1-amine
  • InChIKey: SETMAZMOXYOEJA-NRFANRHFSA-N
  • SMILES: CN(CC[C@H]1CC2=C(CC1)C=C(C=C2)OCC3=CC=C(C=C3)C4=CC=CC=C4)C

Biological Activity: TAK-070 Free base is a noncompetitive and orally active BACE1 inhibitor (IC50: 3.15 μM). TAK-070 Free base can be used for research of Alzheimer’s disease (AD). TAK-070 Free base inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model[1].

Cat. No. Product Name Purity Description
HY-114234A TAK-070 Free base TAK-070 Free base is a noncompetitive and orally active BACE1 inhibitor (IC50: 3.15 μM). TAK-070 Free base can be used for research of Alzheimer’s disease (AD). TAK-070 Free base inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model.

References

Keywords:

TAK-070 Free base