2. Metabolic Enzyme/Protease Protein Tyrosine Kinase/RTK PI3K/Akt/mTOR
  3. Phosphatase Insulin Receptor Akt
  4. 1628448-77-0

1628448-77-0

GPR120 Agonist 1 Chemical Structure

1628448-77-0

Chemical Structure

  • GPR120 Agonist 1
  • CAS No: 1628448-77-0
    Formula: C20H12ClF6NO3S
    Molecular Weight: 495.82
  • IUPAC Name: 3-(4-((3-(4-chloro-2-fluorophenyl)-5-(trifluoromethyl)isothiazol-4-yl)methoxy)-3,5-difluorophenyl)propanoic acid
  • InChIKey: PSUHZRYVUSVFCF-UHFFFAOYSA-N
  • SMILES: ClC1=CC(F)=C(C2=NSC(C(F)(F)F)=C2COC3=C(F)C=C(CCC(O)=O)C=C3F)C=C1

Biological Activity: GPR120 Agonist 1 is a potent and selective GPR120 agonist, and possesses promising antidiabetic effect and good safety profile to be a development candidate[1].

Cat. No. Product Name Purity Description
HY-108711 GPR120 Agonist 1 GPR120 Agonist 1 is a potent and selective GPR120 agonist, and possesses promising antidiabetic effect and good safety profile to be a development candidate.

References

[1]. Zhang X, et al. Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes. ACS Med Chem Lett. 2017 Jul 27;8(9):947-952. [Content Brief]

Keywords:

GPR120 Agonist 1