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  4. 169209-66-9

169209-66-9

MTPG Chemical Structure

169209-66-9

Chemical Structure

  • MTPG
  • CAS No: 169209-66-9
    Formula: C10H11N5O2
    Molecular Weight: 233.23
  • IUPAC Name: 2-(4-(1H-tetrazol-5-yl)phenyl)-2-aminopropanoic acid
  • InChIKey: OZBFBAYESADVDX-UHFFFAOYSA-N
  • SMILES: O=C(O)C(C)(N)C1=CC=C(C2=NN=NN2)C=C1

Biological Activity: MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release[1].

Cat. No. Product Name Purity Description
HY-101247 MTPG MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release.

References

[1]. Chaki S, et al. Group II metabotropic glutamate receptor-mediated regulation of dopamine release from slices of rat nucleus accumbens. Neurosci Lett. 2006;404(1-2):182-186. [Content Brief]

Keywords:

MTPG