2. PROTAC
  3. Ligands for E3 Ligase
  4. 2389988-43-4

2389988-43-4

7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine Chemical Structure

2389988-43-4

Chemical Structure

  • 7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine
  • CAS No: 2389988-43-4
    Formula: C12H17N5O6
    Molecular Weight: 327.29
  • IUPAC Name: 2-amino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7-ethyl-7,9-dihydro-3H-purine-6,8-dione
  • InChIKey: ZEGPMVJWAGPKJX-GAWUUDPSSA-N
  • SMILES: OC[C@@H]1[C@H](O)[C@@H](O)[C@H](N2C(N(CC)C3=C2NC(N)=NC3=O)=O)O1

Biological Activity: 7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cat. No. Product Name Purity Description
HY-152328 7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine 7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Keywords:

7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine