2. Epigenetics PROTAC
  3. Epigenetic Reader Domain Ligands for Target Protein for PROTAC
  4. 2313230-51-0

2313230-51-0

PROTAC BRD4 ligand-1 Chemical Structure

2313230-51-0

Chemical Structure

  • PROTAC BRD4 ligand-1
  • CAS No: 2313230-51-0
    Formula: C23H18F2N4O5S
    Molecular Weight: 500.47
  • IUPAC Name: 7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxylic acid
  • InChIKey: BSYGSSMAXOMCQE-UHFFFAOYSA-N
  • SMILES: O=C(C1=C(CS(=O)(C)=O)C=C(C(N(C2=NC=C(F)C=C2F)C3)=C1)C4=CN(C)C(C5=C4C3=CN5)=O)O

Biological Activity: PROTAC BRD4 ligand-1 is a potent BET inhibitor and a ligand for target BRD4 protein for PROTACT GNE-987 (HY-129937A)[1].

Cat. No. Product Name Purity Description
HY-129939 PROTAC BRD4 ligand-1 99.85% PROTAC BRD4 ligand-1 is a potent BET inhibitor and a ligand for target BRD4 protein for PROTACT GNE-987 (HY-129937A).

References

[1]. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31. [Content Brief]

Keywords:

PROTAC BRD4 ligand-1