2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 921605-87-0

921605-87-0

MF-438 Chemical Structure

921605-87-0

Chemical Structure

  • MF-438
  • CAS No: 921605-87-0
    Formula: C19H18F3N5OS
    Molecular Weight: 421.44
  • IUPAC Name: 2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl)pyridazin-3-yl)-1,3,4-thiadiazole
  • InChIKey: NVUJDKDVOZVALT-UHFFFAOYSA-N
  • SMILES: FC(C1=CC=CC=C1OC2CCN(C3=NN=C(C4=NN=C(C)S4)C=C3)CC2)(F)F

Biological Activity: MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an IC50 of 2.3 nM for rSCD1[1].

Cat. No. Product Name Purity Description
HY-15822 MF-438 99.86% MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an IC50 of 2.3 nM for rSCD1.

References

[1]. Léger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502. [Content Brief]

Keywords:

MF-438