2. Epigenetics
  3. Epigenetic Reader Domain
  4. 1231243-91-6

1231243-91-6

DGAT-1 inhibitor 3 Chemical Structure

1231243-91-6

Chemical Structure

  • DGAT-1 inhibitor 3
  • CAS No: 1231243-91-6
    Formula: C21H20F3N3O3
    Molecular Weight: 419.40
  • IUPAC Name: N-(4-((2-methoxyethyl)(methyl)amino)phenyl)-2-phenyl-5-(trifluoromethyl)oxazole-4-carboxamide
  • InChIKey: GLLFNZDVMSLOCL-UHFFFAOYSA-N
  • SMILES: O=C(C1=C(C(F)(F)F)OC(C2=CC=CC=C2)=N1)NC3=CC=C(N(CCOC)C)C=C3

Biological Activity: DGAT-1 inhibitor 3 (compound 10) is a potent DGAT-1 inhibitor with an IC50 value of 0.038 µM. DGAT-1 inhibitor 3 has the potential for the research of obesity and diabetes[1].

Cat. No. Product Name Purity Description
HY-136707 DGAT-1 inhibitor 3 DGAT-1 inhibitor 3 (compound 10) is a potent DGAT-1 inhibitor with an IC50 value of 0.038 µM. DGAT-1 inhibitor 3 has the potential for the research of obesity and diabetes.

References

[1]. Qian Y, et al. Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes. J Med Chem. 2011 Apr 14;54(7):2433-46. [Content Brief]

Keywords:

DGAT-1 inhibitor 3