2. Others
  3. Others Isotope-Labeled Compounds
  4. 2410277-60-8

2410277-60-8

Isoallolithocholic acid-d<sub>4</sub> Chemical Structure

2410277-60-8

Chemical Structure

  • Isoallolithocholic acid-d4
  • Synonym(s): 3β-Hydroxy-5α-cholanic acid-d4
  • CAS No: 2410277-60-8
    Formula: C24H36D4O3
    Molecular Weight: 380.60
  • SMILES: C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@@](C([2H])([2H])[C@H](C([2H])([2H])C4)O)([H])CC3)C

Biological Activity: Isoallolithocholic acid-d4 (3β-Hydroxy-5α-cholanic acid-d4) is deuterium labeled Isoallolithocholic acid. Isoallolithocholic acid (3β-Hydroxy-5α-cholanic acid), a derivative of Lithocholic acid (HY-10219), is a T cell regulator. Isoallolithocholic acid enhances regulatory T cells (Tregs) differentiation[1][2].

Cat. No. Product Name Purity Description
HY-B0172AS1 Isoallolithocholic acid-d4 Isoallolithocholic acid-d4 (3β-Hydroxy-5α-cholanic acid-d4) is deuterium labeled Isoallolithocholic acid. Isoallolithocholic acid (3β-Hydroxy-5α-cholanic acid), a derivative of Lithocholic acid (HY-10219), is a T cell regulator. Isoallolithocholic acid enhances regulatory T cells (Tregs) differentiation.

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Hang S, et al. Bile acid metabolites control TH17 and Treg cell differentiation. Nature. 2019 Dec;576(7785):143-148. [Content Brief]

Keywords:

Isoallolithocholic acid-d4