2. Anti-infection
  3. Beta-lactamase Bacterial
  4. 2410688-61-6

2410688-61-6

ANT3310 sodium Chemical Structure

2410688-61-6

Chemical Structure

  • ANT3310 sodium
  • CAS No: 2410688-61-6
    Formula: C6H8FN2NaO5S
    Molecular Weight: 262.19
  • IUPAC Name: sodium (1S,2R,5R)-2-fluoro-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate
  • InChIKey: UIJIKXQAJBMNIR-JBUOLDKXSA-M
  • SMILES: O=S(ON1[C@H]2C[N@]([C@@H](CC2)F)C1=O)(O[Na])=O

Biological Activity: ANT3310 sodium is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC50 values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase). ANT3310 sodium potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). ANT3310 sodium can be used in the research of bacterial infection[1][2].

Cat. No. Product Name Purity Description
HY-147349 ANT3310 sodium 99.54% ANT3310 sodium is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC50 values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase). ANT3310 sodium potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). ANT3310 sodium can be used in the research of bacterial infection.

References

[1]. David T Davies, et al. Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii. J Med Chem. 2020 Dec 24;63(24):15802-15820. [Content Brief]

Keywords:

ANT3310 sodium