2. Metabolic Enzyme/Protease
  3. UGT
  4. 862772-11-0

862772-11-0

Cyclo(Arg-Gly-Asp-D-Phe-Cys) Chemical Structure

862772-11-0

Chemical Structure

  • Cyclo(Arg-Gly-Asp-D-Phe-Cys)
  • Synonym(s): Cyclo(RGDfC)
  • CAS No: 862772-11-0
    Formula: C24H34N8O7S
    Molecular Weight: 578.64
  • InChIKey: WNYJVAMZRBTOPE-YVSFHVDLSA-N
  • SMILES: O=C([C@@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC(CNC2=O)=O)=O)N[C@@H](CS)C(N[C@H]2CCCNC(N)=N)=O

Biological Activity: Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors[1].

Cat. No. Product Name Purity Description
HY-P2300 Cyclo(Arg-Gly-Asp-D-Phe-Cys) 99.70% Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors.

References

[1]. Hazenbiller O, et al. Reduction of pluripotent gene expression in murine embryonic stem cells exposed to mechanical loading or Cyclo RGD peptide. BMC Cell Biol. 2017 Nov 14;18(1):32. [Content Brief]

Keywords:

Cyclo(Arg-Gly-Asp-D-Phe-Cys)