2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. 125787-94-2

125787-94-2

FK224 Chemical Structure

125787-94-2

Chemical Structure

  • FK224
  • CAS No: 125787-94-2
    Formula: C54H72N8O13
    Molecular Weight: 1041.20
  • IUPAC Name: N-((3S,6S,9S,12R,15S,21S,22R)-6-(2-amino-2-oxoethyl)-12-benzyl-18-((E)-4-hydroxybenzylidene)-9-((S)-1-hydroxyethyl)-3-(hydroxymethyl)-15-isobutyl-19,22-dimethyl-2,5,8,11,14,17,20-heptaoxo-1-oxa-4,7,10,13,16,19-hexaazacyclodocosan-21-yl)-3-(2-pentylphenyl)
  • InChIKey: BEWCDVTWUFJSSM-VMRJGJBNSA-N
  • SMILES: CN(C([C@H]([C@H](OC([C@@H](NC([C@@H](NC([C@](NC([C@H](NC([C@@H](NC/1=O)CC(C)C)=O)CC2=CC=CC=C2)=O)([H])[C@@H](O)C)=O)CC(N)=O)=O)CO)=O)C)NC(CCC3=C(C=CC=C3)CCCCC)=O)=O)C1=C\C4=CC=C(C=C4)O

Biological Activity: FK224 is a tachykinin receptor antagonist. FK224 reduces the tracheal plasma extravasation induced by substance P (SP) and neurokinin A (NKA)[1].

Cat. No. Product Name Purity Description
HY-105264 FK224 FK224 is a tachykinin receptor antagonist. FK224 reduces the tracheal plasma extravasation induced by substance P (SP) and neurokinin A (NKA).

References

[1]. Morimoto H, et al. Effects of FR 113680 and FK 224, novel tachykinin receptor antagonists, on cigarette smoke-induced rat tracheal plasma extravasation. Eur J Pharmacol. 1992 Nov 24;224(1):1-5. [Content Brief]

Keywords:

FK224