2. Immunology/Inflammation Apoptosis
  3. IRAK Apoptosis
  4. 756525-91-4

756525-91-4

Boc-NH-PEG4-CH2CH2COOH Chemical Structure

756525-91-4

Chemical Structure

  • Boc-NH-PEG4-CH2CH2COOH
  • CAS No: 756525-91-4
    Formula: C16H31NO8
    Molecular Weight: 365.42
  • IUPAC Name: 2,2-dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oic acid
  • InChIKey: YEIYIPDFZMLJQH-UHFFFAOYSA-N
  • SMILES: CC(C)(OC(NCCOCCOCCOCCOCCC(O)=O)=O)C

Biological Activity: Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1]. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[2].

Cat. No. Product Name Purity Description
HY-W040132 Boc-NH-PEG4-CH2CH2COOH 99.85% Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).

References

[1]. Nathanael Gray, et al. Bifunctional compounds for her3 degradation and methods of use. WO2018114798A1.
[2]. Hans-Georg Lerchen, et al. Prodrugs of cytotoxic active agents having enzymatically cleavable groups. WO2018114798A1.

Keywords:

Boc-NH-PEG4-CH2CH2COOH