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  3. Fluorescent Dye
  4. 2639638-66-5

2639638-66-5

BAY-069 Chemical Structure

2639638-66-5

Chemical Structure

  • BAY-069
  • CAS No: 2639638-66-5
    Formula: C22H14ClF3N2O3
    Molecular Weight: 446.81
  • IUPAC Name: 3-(4-chloro-3-(o-tolyloxy)naphthalen-1-yl)-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione
  • InChIKey: UNSHMXUHOHBLIQ-UHFFFAOYSA-N
  • SMILES: CC(C=CC=C1)=C1OC2=C(Cl)C3=C(C=CC=C3)C(N4C(NC(C(F)(F)F)=CC4=O)=O)=C2

Biological Activity: BAY-069 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50 values of 31 nM and 153 nM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used tor research anticancer[1].

Cat. No. Product Name Purity Description
HY-148242 BAY-069 99.58% BAY-069 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50 values of 31 nM and 153 nM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used tor research anticancer.

References

[1]. Günther J, et al. BAY-069, a Novel (Trifluoromethyl)pyrimidinedione-Based BCAT1/2 Inhibitor and Chemical Probe. J Med Chem. 2022 Oct 19. [Content Brief]

Keywords:

BAY-069