2. Metabolic Enzyme/Protease
  3. Indoleamine 2,3-Dioxygenase (IDO)
  4. 1333154-77-0

1333154-77-0

Azido-PEG7-amine Chemical Structure

1333154-77-0

Chemical Structure

  • Azido-PEG7-amine
  • CAS No: 1333154-77-0
    Formula: C16H34N4O7
    Molecular Weight: 394.46
  • IUPAC Name: 23-azido-3,6,9,12,15,18,21-heptaoxatricosan-1-amine
  • InChIKey: VZKXLNRXAFTBOW-UHFFFAOYSA-N
  • SMILES: NCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Biological Activity: Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG7-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG7-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No. Product Name Purity Description
HY-130324 Azido-PEG7-amine ≥95.0% Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG7-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG7-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1]. Kevin W. Gillman, et al. Macrocyclic peptides useful as immunomodulators. WO2016077518A1.

Keywords:

Azido-PEG7-amine