2. Antibody-drug Conjugate/ADC Related
  3. Radionuclide-Drug Conjugates (RDCs)
  4. 2740747-99-1

2740747-99-1

(S)-EB-FAPI-B2 Chemical Structure

2740747-99-1

Chemical Structure

  • (S)-EB-FAPI-B2
  • CAS No: 2740747-99-1
    Formula: C78H100N16O22S2
    Molecular Weight: 1677.85
  • InChIKey: UPKLEJRVHWNAEQ-LAHOEMNUSA-N
  • SMILES: O=S(O)(C1=CC(S(=O)(O)=O)=C(N)C2=C1C=CC(/N=N/C3=C(C=C(C4=CC(C)=C(C=C4)NC([C@H](CCCCNC(CCOCCOCCC(N5CCN(CC5)CCCOC6=CC7=C(N=CC=C7C(NCC(N8[C@@H](CCC8)C#N)=O)=O)C=C6)=O)=O)NC(CN9CCN(CCN(CCN(CC9)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)C=C3)C)=C2O)=O

Biological Activity: (S)-EB-FAPI-B2 (Compound II-11) is a precursor for radiopharmaceutical labeling, which can be combined with radionuclides to create radionuclide drug conjugates (RDCs). RDCs have the capability to specifically target biomolecules and can be used in medical imaging or therapy[1][2].

Cat. No. Product Name Purity Description
HY-159770A (S)-EB-FAPI-B2 (S)-EB-FAPI-B2 (Compound II-11) is a precursor for radiopharmaceutical labeling, which can be combined with radionuclides to create radionuclide drug conjugates (RDCs). RDCs have the capability to specifically target biomolecules and can be used in medical imaging or therapy.

References

[1]. Chen XY, et al. Truncated Evans blue modified fibroblast activation protein inhibitor and preparation method and application thereof. CN113582975A. 2021 November 02.
[2]. Wen X, et al. Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics. Theranostics. 2022 Jan 1;12(1):422-433. [Content Brief]

Keywords:

(S)-EB-FAPI-B2