2. Cell Cycle/DNA Damage
  3. CDK
  4. 2745060-92-6

2745060-92-6

INX-315 Chemical Structure

2745060-92-6

Chemical Structure

  • INX-315
  • CAS No: 2745060-92-6
    Formula: C19H21N7O3S
    Molecular Weight: 427.48
  • InChIKey: KGJVKYSVVOQPDL-UHFFFAOYSA-N
  • SMILES: O=C(NN1)C2(CCCCC2)N(C1=C3)C4=C3C=NC(NC5=CC=C(S(=O)(N)=O)C=C5)=N4

Biological Activity: INX-315 is an orally active and selective CDK2 inhibitor that induces cell cycle arrest in the G1 phase. INX-315 reduces CDK2 substrate phosphorylation and inhibits tumor growth in a dose-dependent manner in xenograft mouse models. INX-315 may be used in cancer research[1].

Cat. No. Product Name Purity Description
HY-162001 INX-315 99.17% INX-315 is an orally active and selective CDK2 inhibitor that induces cell cycle arrest in the G1 phase. INX-315 reduces CDK2 substrate phosphorylation and inhibits tumor growth in a dose-dependent manner in xenograft mouse models. INX-315 may be used in cancer research.

References

[1]. Dietrich C, et al. INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors. Cancer Discov. 2023 Dec 4. [Content Brief]

Keywords:

INX-315