1. GPCR/G Protein MAPK/ERK Pathway
  2. Ras
  3. 2749963-77-5

2749963-77-5

KRAS G12C inhibitor 56 Chemical Structure

2749963-77-5

Chemical Structure

  • KRAS G12C inhibitor 56
  • CAS No: 2749963-77-5
    Formula: C32H39N7O4S
    Molecular Weight: 617.76
  • IUPAC Name: (S)-4-(5-(4-((1-acryloylpiperidin-4-yl)oxy)-6-((S)-1-((S)-1-methylpyrrolidin-2-yl)ethoxy)pyrimidin-2-yl)isoxazol-3-yl)-2-amino-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile
  • InChIKey: VPGFGUVVEBRZJS-RKGKDDSLSA-N
  • SMILES: C=CC(N1CCC(CC1)OC2=NC(C3=CC([C@@]4(C)CCCC5=C4C(C#N)=C(S5)N)=NO3)=NC(O[C@H]([C@@H]6CCCN6C)C)=C2)=O

Biological Activity: KRAS G12C inhibitor 56 (compound IC-6) is a potent SOS1 inhibitor with an IC50 of 1.6 nM. KRAS G12C inhibitor 56 can be used in cancer research[1].

Cat. No. Product Name Purity Description
HY-148261 KRAS G12C inhibitor 56 KRAS G12C inhibitor 56 (compound IC-6) is a potent SOS1 inhibitor with an IC50 of 1.6 nM. KRAS G12C inhibitor 56 can be used in cancer research.

References