2. Protein Tyrosine Kinase/RTK
  3. Btk
  4. 2562329-13-7

2562329-13-7

(S)-Cdc7-IN-18 Chemical Structure

2562329-13-7

Chemical Structure

  • (S)-Cdc7-IN-18
  • CAS No: 2562329-13-7
    Formula: C19H21N5OS
    Molecular Weight: 367.47
  • IUPAC Name: (S)-8-(quinuclidin-2-yl)-2,4,5,6-tetrahydropyrazolo[4'',3'':3',4']cyclohepta[1',2':4,5]thieno[3,2-d]pyrimidin-10(7H)-one
  • InChIKey: MJWWMBBHELJWLE-AWEZNQCLSA-N
  • SMILES: O=C1C2=C(NC([C@@]3([H])N4CCC(CC4)C3)=N1)C5=C(C6=CNN=C6CCC5)S2

Biological Activity: (S)-Cdc7-IN-18 is a potent inhibitor of CDC7. Overexpression of huCdc7 promotes overactivation of MCM2, an important marker of tumor cells, and thus promotes aberrant proliferation of tumor cells. (S)-Cdc7-IN-18 has the potential for the research of cancer diseases (extracted from patent WO2020239107A1, compound 1-1)[1].

Cat. No. Product Name Purity Description
HY-143432A (S)-Cdc7-IN-18 (S)-Cdc7-IN-18 is a potent inhibitor of CDC7. Overexpression of huCdc7 promotes overactivation of MCM2, an important marker of tumor cells, and thus promotes aberrant proliferation of tumor cells. (S)-Cdc7-IN-18 has the potential for the research of cancer diseases (extracted from patent WO2020239107A1, compound 1-1).

References

[1]. Gang Li, et al. Tetracyclines as Cdc7 inhibitors. Patent WO2020239107A1.

Keywords:

(S)-Cdc7-IN-18