2761734-27-2

Chemical Structure

DNA crosslinker 1 dihydrochloride
CAS No: 2761734-27-2

Formula: C₁₅H₂₂Cl₂N₈O

Molecular Weight: 401.29
IUPAC Name: 1-(4-((5-(guanidinomethyl)-6-oxopyridazin-1(6H)-yl)methyl)benzyl)guanidine dihydrochloride
InChIKey: WVCNOKXJAKGIOH-UHFFFAOYSA-N
SMILES: N=C(NCC1=CC=C(C=C1)CN2N=CC=C(C2=O)CNC(N)=N)N.[H]Cl.[H]Cl

Biological Activity: DNA crosslinker 1 dihydrochloride (Compound 4) is a potent DNA minor groove binder with DNA binding affinity (ΔT_m) of 1.1 °C. DNA crosslinker 1 dihydrochloride can be used for researching anticancer^[1].

Cat. No.	Product Name	Purity	Description
HY-144333	DNA crosslinker 1 dihydrochloride		DNA crosslinker 1 dihydrochloride (Compound 4) is a potent DNA minor groove binder with DNA binding affinity (ΔT_m) of 1.1 °C. DNA crosslinker 1 dihydrochloride can be used for researching anticancer.

References

[1]. Costas-Lago MC, et al. Novel Pyridazin-3(2H)-one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity. ACS Med Chem Lett. 2022;13(3):463-469. Published 2022 Feb 10. [Content Brief]

Keywords:

DNA crosslinker 1 dihydrochloride

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