1227675-52-6

Chemical Structure

MNI-caged-NMDA
CAS No: 1227675-52-6

Formula: C₁₄H₁₇N₃O₆

Molecular Weight: 323.30
IUPAC Name: (R)-4-(4-methoxy-7-nitroindolin-1-yl)-2-(methylamino)-4-oxobutanoic acid
InChIKey: MUCRWOILMOHLGD-SECBINFHSA-N
SMILES: O=C(O)[C@H](NC)CC(N1CCC2=C1C([N+]([O-])=O)=CC=C2OC)=O

Biological Activity: MNI-caged-NMDA is a light-sensitive amino acid with rapid release properties suitable for use in the study of fast synaptic receptor mechanisms. MNI-caged-NMDA shows metered release of NMDA receptors, inducing rapid and sustained receptor activation in cerebellar interneurons. MNI-caged-NMDA is able to achieve rapid transient responses and generate large inward currents by local laser photolysis. The use of MNI-caged-NMDA can effectively study neurotransmitter signaling and its inhibitory effects on GABA-A receptors^[1].

Cat. No.	Product Name	Purity	Description
HY-107717	MNI-caged-NMDA		MNI-caged-NMDA is a light-sensitive amino acid with rapid release properties suitable for use in the study of fast synaptic receptor mechanisms. MNI-caged-NMDA shows metered release of NMDA receptors, inducing rapid and sustained receptor activation in cerebellar interneurons. MNI-caged-NMDA is able to achieve rapid transient responses and generate large inward currents by local laser photolysis. The use of MNI-caged-NMDA can effectively study neurotransmitter signaling and its inhibitory effects on GABA-A receptors.

References

[1]. New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups

Keywords:

MNI-caged-NMDA

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