2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. ROR Dihydroorotate Dehydrogenase
  4. 2243701-11-1

2243701-11-1

Dyrk1A-IN-12 Chemical Structure

2243701-11-1

Chemical Structure

  • Dyrk1A-IN-12
  • CAS No: 2243701-11-1
    Formula: C22H16FN3O2S
    Molecular Weight: 405.44
  • SMILES: O=C(C1=CC(OC)=CC=C1F)NC2=CN=CC(C3=CC(C4=CC=CN=C4)=CS3)=C2

Biological Activity: Dyrk1A-IN-12 (compound S43) is a Dyrk (Dual specificity tyrosine phosphorylation regulated kinase 1A inhibitor. Dyrk1A-IN-12 inhibits Dyrk1A with a IC50 of 95 nM. Dyrk1A-IN-12 shows anti-EV-A71 activity with an EC50 of 4.4 μM, CC50 of 12.8 μM and SI of 2.9. Dyrk1A-IN-12 shows potent inhibition against herpes simplex virus (HSV)[1].

Cat. No. Product Name Purity Description
HY-170940 Dyrk1A-IN-12 Dyrk1A-IN-12 (compound S43) is a Dyrk (Dual specificity tyrosine phosphorylation regulated kinase 1A inhibitor. Dyrk1A-IN-12 inhibits Dyrk1A with a IC50 of 95 nM. Dyrk1A-IN-12 shows anti-EV-A71 activity with an EC50 of 4.4 μM, CC50 of 12.8 μM and SI of 2.9. Dyrk1A-IN-12 shows potent inhibition against herpes simplex virus (HSV).

Keywords:

Dyrk1A-IN-12