2. Anti-infection
  3. Fungal
  4. 2577288-83-4

2577288-83-4

CDK4/9-IN-1 Chemical Structure

2577288-83-4

Chemical Structure

  • CDK4/9-IN-1
  • CAS No: 2577288-83-4
    Formula: C22H34N6O2
    Molecular Weight: 414.54
  • SMILES: CN(C)C(C(N(C1CCCC1)C2=N3)=CC2=CN=C3N[C@@H]4CC[C@H](CC4)NCCO)=O

Biological Activity: CDK4/9-IN-1 (Compound 29) is a selective dual CDK4/9 inhibitor with IC50 values of 23 nM and 12 nM, respectively. CDK4/9-IN-1 is promising for research of cancers[1].

Cat. No. Product Name Purity Description
HY-170815 CDK4/9-IN-1 CDK4/9-IN-1 (Compound 29) is a selective dual CDK4/9 inhibitor with IC50 values of 23 nM and 12 nM, respectively. CDK4/9-IN-1 is promising for research of cancers.

References

[1]. Jiang C, et al. Elucidating Binding Selectivity in Cyclin-Dependent Kinases 4, 6, and 9: Development of Highly Potent and Selective CDK4/9 Inhibitors. J Med Chem. 2025 Jan 23;68(2):1499-1510. [Content Brief]

Keywords:

CDK4/9-IN-1