1. GPCR/G Protein MAPK/ERK Pathway
  2. Ras
  3. 2590556-80-0

2590556-80-0

M4205 Chemical Structure

2590556-80-0

Chemical Structure

  • M4205
  • Synonym(s): IDRX-42
  • CAS No: 2590556-80-0
    Formula: C29H32N8O
    Molecular Weight: 508.62
  • IUPAC Name: N-(4-(1-methyl-1H-pyrazol-4-yl)benzyl)-6-(7-(3-(pyrrolidin-1-yl)propoxy)imidazo[1,2-a]pyridin-3-yl)pyrimidin-4-amine
  • InChIKey: LVMAULGVWBINFP-UHFFFAOYSA-N
  • SMILES: CN1N=CC(C2=CC=C(CNC3=NC=NC(C4=CN=C5C=C(C=CN54)OCCCN6CCCC6)=C3)C=C2)=C1

Biological Activity: M4205 is a multi-target inhibitor for PDGFRB, PDGFRA, CSF1R, c-Kit, FLT3, and LCK, with an IC50s of 2.6, 50, 5.5, 44, 141 and 141 nM, respectively. M4205 exhibits antitumor efficacy in xenograft mouse models[1].

Cat. No. Product Name Purity Description
HY-132166 M4205 99.47% M4205 is a multi-target inhibitor for PDGFRB, PDGFRA, CSF1R, c-Kit, FLT3, and LCK, with an IC50s of 2.6, 50, 5.5, 44, 141 and 141 nM, respectively. M4205 exhibits antitumor efficacy in xenograft mouse models.

References

Keywords:

M4205