2. Metabolic Enzyme/Protease GPCR/G Protein
  3. Phosphodiesterase (PDE) LPL Receptor
  4. 2800898-98-8

2800898-98-8

Autotaxin-IN-6 Chemical Structure

2800898-98-8

Chemical Structure

  • Autotaxin-IN-6
  • CAS No: 2800898-98-8
    Formula: C35H54BNO6
    Molecular Weight: 595.62
  • IUPAC Name: (4-((1-((R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoyl)piperidin-4-yl)oxy)phenyl)boronic acid
  • InChIKey: ZIFDOLGFKFUTEG-KSZJEZMCSA-N
  • SMILES: O[C@@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCC(N4CCC(CC4)OC5=CC=C(C=C5)B(O)O)=O)C)([H])[C@@]6([C@](C[C@@H](CC6)O)([H])C1)C

Biological Activity: Autotaxin-IN-6 (compound 23) is a potent autotaxin (ATX) inhibitor with an IC50 value of 30 nM. Autotaxin-IN-6 can reduce cell migration. Autotaxin-IN-6 can be used for researching anticancer[1].

Cat. No. Product Name Purity Description
HY-150614 Autotaxin-IN-6 Autotaxin-IN-6 (compound 23) is a potent autotaxin (ATX) inhibitor with an IC50 value of 30 nM. Autotaxin-IN-6 can reduce cell migration. Autotaxin-IN-6 can be used for researching anticancer.

References

[1]. Clark JM, et al. Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators. J Med Chem. 2022 Apr 28;65(8):6338-6351. [Content Brief]

Keywords:

Autotaxin-IN-6