1. Metabolic Enzyme/Protease
  2. Cytochrome P450
  3. 2302046-54-2

2302046-54-2

HIV-1 inhibitor-27 Chemical Structure

2302046-54-2

Chemical Structure

  • HIV-1 inhibitor-27
  • CAS No: 2302046-54-2
    Formula: C46H78N2O7
    Molecular Weight: 771.12
  • IUPAC Name: (3S,4S)-3-hydroxy-4-(8-((4aS,6aR,6bR,8aR,10S,12aR,12bR,14aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-14-oxodocosahydropicene-4a-carboxamido)octanamido)-6-methylheptanoic acid
  • InChIKey: BNUZALUKJXRLPV-IBKCJNAWSA-N
  • SMILES: [H][C@@]12CC(C)(CC[C@@]1(CC[C@@]3([C@@]2(C(C[C@@]4([C@]5(CC[C@@H](C(C)([C@@]5(CC[C@]43C)[H])C)O)C)[H])=O)[H])C)C(NCCCCCCCC(N[C@H]([C@H](CC(O)=O)O)CC(C)C)=O)=O)C

Biological Activity: HIV-1 inhibitor-27 (compound 5) is a potent HIV-1 inhibitor with IC50s of 16 μM, 0.5 μM and 0.39 μM for HIV-1 YU2, NL4-3 and 89.6 strain, respectively. HIV-1 inhibitor-27 has low cytotoxicity with a CC50 of 128 μM in TZM-bl cells. HIV-1 inhibitor-27 can be used for researching AIDS[1].

Cat. No. Product Name Purity Description
HY-146339 HIV-1 inhibitor-27 HIV-1 inhibitor-27 (compound 5) is a potent HIV-1 inhibitor with IC50s of 16 μM, 0.5 μM and 0.39 μM for HIV-1 YU2, NL4-3 and 89.6 strain, respectively. HIV-1 inhibitor-27 has low cytotoxicity with a CC50 of 128 μM in TZM-bl cells. HIV-1 inhibitor-27 can be used for researching AIDS.

References

Keywords:

HIV-1 inhibitor-27