1. Protein Tyrosine Kinase/RTK Autophagy
  2. VEGFR Autophagy PDGFR
  3. 288383-20-0

288383-20-0

Cediranib Chemical Structure

288383-20-0

Chemical Structure

  • Cediranib
  • Synonym(s): AZD2171
  • CAS No: 288383-20-0
    Formula: C25H27FN4O3
    Molecular Weight: 450.51
  • IUPAC Name: 4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline
  • InChIKey: XXJWYDDUDKYVKI-UHFFFAOYSA-N
  • SMILES: FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5

Biological Activity: Cediranib (AZD2171) is a highly potent, orally available VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.

Cat. No. Product Name Purity Description
HY-10205 Cediranib 99.38% Cediranib (AZD2171) is a highly potent, orally available VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.
HY-10205R Cediranib (Standard) ≥98% Cediranib (Standard) is the analytical standard of Cediranib. This product is intended for research and analytical applications. Cediranib (AZD2171) is a highly potent, orally available VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.