1. Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  2. PD-1/PD-L1 Toll-like Receptor (TLR) Drug-Linker Conjugates for ADC
  3. 2939851-67-7

2939851-67-7

HE-S2 Chemical Structure

2939851-67-7

Chemical Structure

  • HE-S2
  • CAS No: 2939851-67-7
    Formula: C38H45N9O6S2
    Molecular Weight: 787.95
  • IUPAC Name: (R)-N-(4-((2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl)methyl)benzyl)-N,N-dimethyl-1-(4-(((2-((5-nitropyridin-2-yl)disulfanyl)propoxy)carbonyl)amino)phenyl)methanaminium formate
  • InChIKey: UNONHPRCWDOFSQ-VQIWEWKSSA-N
  • SMILES: C[C@H](COC(NC1=CC=C(C[N+](C)(C)CC2=CC=C(CC3=CC=C(N=C(N)N=C4NCCCC)C4=N3)C=C2)C=C1)=O)SSC5=NC=C([N+]([O-])=O)C=C5.[H]C([O-])=O

Biological Activity: HE-S2 is an antibody-drug conjugate triggering a potent antitumor immune response. HE-S2 acts by blocking the PD-1/PD-L1 interaction and activating the Toll-like receptor 7/8 (TLR7/8) signaling pathway. HE-S2 has remarkable antitumor activity[1].

Cat. No. Product Name Purity Description
HY-144497 HE-S2 HE-S2 is an antibody-drug conjugate triggering a potent antitumor immune response. HE-S2 acts by blocking the PD-1/PD-L1 interaction and activating the Toll-like receptor 7/8 (TLR7/8) signaling pathway. HE-S2 has remarkable antitumor activity.

References

Keywords:

HE-S2