2. Protein Tyrosine Kinase/RTK
  3. TAM Receptor
  4. 1092689-33-2

1092689-33-2

Tetrazine-Amine Chemical Structure

1092689-33-2

Chemical Structure

  • Tetrazine-Amine
  • Synonym(s): (4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine; Tetrazine-NH2
  • CAS No: 1092689-33-2
    Formula: C9H9N5
    Molecular Weight: 187.20
  • IUPAC Name: (4-(1,2,4,5-tetrazin-3-yl)phenyl)methanamine
  • InChIKey: JGCOJRPYFRRONJ-UHFFFAOYSA-N
  • SMILES: NCC1=CC=C(C2=NN=CN=N2)C=C1

Biological Activity: Tetrazine-Amine is a tetrazine linker that can be used to covalently label live cells through a cycloaddition[1][2]. Tetrazine-Amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

Cat. No. Product Name Purity Description
HY-W899002 CRBN ligand-108 CRBN ligand-108 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.

References

[1]. Devaraj NK, et, al. Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition. Angew Chem Int Ed Engl. 2009;48(38):7013-6. [Content Brief]
[2]. Devaraj NK, et, al. Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjug Chem. 2008 Dec;19(12):2297-9. [Content Brief]

Keywords:

Tetrazine-Amine