2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. 3038811-77-4

3038811-77-4

AChE-IN-41 Chemical Structure

3038811-77-4

Chemical Structure

  • AChE-IN-41
  • CAS No: 3038811-77-4
    Formula: C32H44N2O3
    Molecular Weight: 504.70
  • InChIKey: MQXBZGXYQPDNAD-GOXCJTMESA-N
  • SMILES: O[C@H]1C=C[C@@]23C(C(CN(C/C=C/CN[C@@]45C[C@]6(C)C[C@@](C5)(C)C[C@@H](C6)C4)CC3)=CC=C7OC)=C7O[C@H]2C1

Biological Activity: AChE-IN-41 (Compound 2) is a compound of the Galantamine Memantine hybrid. AChE-IN-41 has the inhibition ability of cholinesterase. AChE-IN-41 shows higher plasma stability and comparable microsomal stability in vitro, while showing lower half-life and faster clearance in vivo[1].

Cat. No. Product Name Purity Description
HY-156188 AChE-IN-41 AChE-IN-41 (Compound 2) is a compound of the Galantamine Memantine hybrid. AChE-IN-41 has the inhibition ability of cholinesterase. AChE-IN-41 shows higher plasma stability and comparable microsomal stability in vitro, while showing lower half-life and faster clearance in vivo.

References

[1]. Basagni F, et al. Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties. Eur J Med Chem. 2023 Sep 12;261:115803. [Content Brief]

Keywords:

AChE-IN-41