2. Cell Cycle/DNA Damage Epigenetics Anti-infection
  3. HDAC Fungal
  4. 3039482-69-1

3039482-69-1

HDAC-IN-87 Chemical Structure

3039482-69-1

Chemical Structure

  • HDAC-IN-87
  • CAS No: 3039482-69-1
    Formula: C13H7F5N4O2S
    Molecular Weight: 378.28
  • SMILES: FC(C1=NC(C2=CC=C(COC3=NC=NC(C(F)F)=C3)S2)=NO1)(F)F

Biological Activity: HDAC-IN-87 (Compound XII6) is a nonselective HDAC inhibitor, with pIC50 of 6.9 (HDAC4) and 5.8 (HDAC6) respectively. HDAC-IN-87 has fungicidal activity against P. sorghi and P. pachyrhizi. HDAC-IN-87 shows an acute oral LD50 of greater than 500 mg/kg in male and female rats[1].

Cat. No. Product Name Purity Description
HY-173053 HDAC-IN-87 HDAC-IN-87 (Compound XII6) is a nonselective HDAC inhibitor, with pIC50 of 6.9 (HDAC4) and 5.8 (HDAC6) respectively. HDAC-IN-87 has fungicidal activity against P. sorghi and P. pachyrhizi. HDAC-IN-87 shows an acute oral LD50 of greater than 500 mg/kg in male and female rats.

References

[1]. Liu XH, et al. Novel 5-(Trifluoromethyl)-1,2,4-oxadiazole-Based Pyrimidin-4-ether Histone Deacetylase Inhibitors for Controlling Rust Disease: Design, Synthesis, Activity, and Structure-Activity Relationship. J Agric Food Chem. 2025 Feb 26;73(8):4563-4573. [Content Brief]

Keywords:

HDAC-IN-87