2. Others Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Cell Cycle/DNA Damage Autophagy
  3. Isotope-Labeled Compounds RAR/RXR PPAR Endogenous Metabolite Autophagy
  4. 1023594-50-4

1023594-50-4

1,1-Dimethylethyl 4-(4-amino-3-pyridinyl)-1-piperazinecarboxylate Chemical Structure

1023594-50-4

Chemical Structure

Biological Activity: 1,1-Dimethylethyl 4-(4-amino-3-pyridinyl)-1-piperazinecarboxylate is the impurity of Palbociclib (HY-50767). Palbociclib is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively[1].

Cat. No. Product Name Purity Description
HY-I0996 1,1-Dimethylethyl 4-(4-amino-3-pyridinyl)-1-piperazinecarboxylate 1,1-Dimethylethyl 4-(4-amino-3-pyridinyl)-1-piperazinecarboxylate is the impurity of Palbociclib (HY-50767). Palbociclib is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively.

References

[1]. Fry DW, et al. Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol Cancer Ther. 2004 Nov;3(11):1427-38. [Content Brief]

Keywords:

1,1-Dimethylethyl 4-(4-amino-3-pyridinyl)-1-piperazinecarboxylate