2. Metabolic Enzyme/Protease
  3. Acyltransferase
  4. 1434515-70-4

1434515-70-4

UCSF924 Chemical Structure

1434515-70-4

Chemical Structure

  • UCSF924
  • CAS No: 1434515-70-4
    Formula: C20H22N2O2
    Molecular Weight: 322.40
  • IUPAC Name: 6-methyl-2-(((3-phenoxypropyl)amino)methyl)quinolin-4-ol
  • InChIKey: RPHDOVLXDYWDGF-UHFFFAOYSA-N
  • SMILES: OC1=CC(CNCCCOC2=CC=CC=C2)=NC3=CC=C(C)C=C13

Biological Activity: UCSF924 is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM. UCSF924 has no off-target effects on more than 320 non-olfactory GPCRs. UCSF924 can be used for research in the field of neuropsychiatric diseases[1][2].

Cat. No. Product Name Purity Description
HY-125751 UCSF924 99.56% UCSF924 is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM. UCSF924 has no off-target effects on more than 320 non-olfactory GPCRs. UCSF924 can be used for research in the field of neuropsychiatric diseases.

References

[1]. Wang S, et al. D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. Science. 2017 Oct 20;358(6361):381-386. [Content Brief]
[2]. Thomas G E. Characterizing antipsychotic behavioral and corticostriatal neurophysiological effects to psychotomimetic challenge. Duke University, 2022.

Keywords:

UCSF924