2. MAPK/ERK Pathway
  3. p38 MAPK
  4. 2753-45-9

2753-45-9

Mebeverine hydrochloride Chemical Structure

2753-45-9

Chemical Structure

  • Mebeverine hydrochloride
  • CAS No: 2753-45-9
    Formula: C25H36ClNO5
    Molecular Weight: 466.01
  • IUPAC Name: 4-(ethyl(1-(4-methoxyphenyl)propan-2-yl)amino)butyl 3,4-dimethoxybenzoate hydrochloride
  • InChIKey: PLGQWYOULXPJRE-UHFFFAOYSA-N
  • SMILES: O=C(OCCCCN(CC)C(C)CC1=CC=C(OC)C=C1)C2=CC=C(OC)C(OC)=C2.[H]Cl

Biological Activity: Mebeverine hydrochloride, a β-phenylethylamine derivative, is a musculotropic agent that potently blocks intestinal peristalsis. Mebeverine directly blocks voltage-operated sodium channels and inhibits intracellular calcium accumulation[1][2].

Cat. No. Product Name Purity Description
HY-A0078R Mebeverine (hydrochloride) (Standard) ≥98% Mebeverine (hydrochloride) (Standard) is the analytical standard of Mebeverine (hydrochloride). This product is intended for research and analytical applications. Mebeverine hydrochloride, a β-phenylethylamine derivative, is a musculotropic agent that potently blocks intestinal peristalsis. Mebeverine directly blocks voltage-operated sodium channels and inhibits intracellular calcium accumulation.
HY-A0078 Mebeverine hydrochloride 99.85% Mebeverine hydrochloride, a β-phenylethylamine derivative, is a musculotropic agent that potently blocks intestinal peristalsis. Mebeverine directly blocks voltage-operated sodium channels and inhibits intracellular calcium accumulation.
HY-A0078S Mebeverine-d6 hydrochloride 0

References

[1]. Annaházi A, et al. Role of antispasmodics in the treatment of irritable bowel syndrome. World J Gastroenterol. 2014;20(20):6031-6043. [Content Brief]
[2]. Den Hertog A, et al. Modification of alpha 1-receptor-operated channels by mebeverine in smooth muscle cells of guinea-pig taenia caeci. Eur J Pharmacol. 1987 Jun 26;138(3):367-74. [Content Brief]

Keywords:

Mebeverine (hydrochloride) (Standard)Mebeverine hydrochlorideMebeverine-d6 hydrochloride