2. Natural Products
  3. Plants Flavonoids
  4. Moraceae Flavonones
  5. Dorstenia mannii Hook.f.
  6. 950403-60-8

950403-60-8

iPAF1C Chemical Structure

950403-60-8

Chemical Structure

  • iPAF1C
  • CAS No: 950403-60-8
    Formula: C27H26BrFN4O
    Molecular Weight: 521.42
  • InChIKey: ZQBFGPMVFJLIPZ-UHFFFAOYSA-N
  • SMILES: O=C(C1CCN(CC1)C2=NC3=C(N2CC4=CC(F)=CC=C4)C=CC=C3)NC5=CC=C(C(C)=C5)Br

Biological Activity: iPAF1C is a potent inhibitor of polymerase-associated factor 1 complex (PAF1C). iPAF1C has anti-HIV activity[1].

Cat. No. Product Name Purity Description
HY-160267 iPAF1C 99.59% iPAF1C is a potent inhibitor of polymerase-associated factor 1 complex (PAF1C). iPAF1C has anti-HIV activity.

References

[1]. Shimaa H A Soliman, et al. Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C. Sci Adv. 2023 Mar 10;9(10):eadf2468. [Content Brief]

Keywords:

iPAF1C