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  4. 4029-65-6

4029-65-6

3-Oxo-bufalin Chemical Structure

4029-65-6

Chemical Structure

  • 3-Oxo-bufalin
  • CAS No: 4029-65-6
    Formula: C24H32O4
    Molecular Weight: 384.51
  • InChIKey: YHPFWEDUGHFFTA-PNERCMSUSA-N
  • SMILES: O[C@@]12[C@@]([C@@H](C(C=C3)=COC3=O)CC1)(CC[C@@]4([H])[C@@]2([H])CC[C@@]5([H])[C@@]4(CCC(C5)=O)C)C

Biological Activity: 3-Oxo-bufalin is an active compound that can be isolated from cultured toad liver tissue. 3-Oxo-bufalin can be produced through a metabolic pathway, and it is a metabolite of Bufalin (HY-N0877) catalyzed by the stereoselective 3β-dehydrogenase. Bufalin is a Na+/K+-ATPase inhibitor and has anti-tumor activity[1].

Cat. No. Product Name Purity Description
HY-N13080 3-Oxo-bufalin 3-Oxo-bufalin is an active compound that can be isolated from cultured toad liver tissue. 3-Oxo-bufalin can be produced through a metabolic pathway, and it is a metabolite of Bufalin (HY-N0877) catalyzed by the stereoselective 3β-dehydrogenase. Bufalin is a Na+/K+-ATPase inhibitor and has anti-tumor activity.

References

[1]. Ruan L J, et al. 3α-Hydroxybufadienolides in Bufo gallbladders: structural insights and biotransformation[J]. Natural Products and Bioprospecting, 2024, 14(1): 19.

Keywords:

3-Oxo-bufalin