2. Metabolic Enzyme/Protease
  3. Thrombin
  4. 892489-52-0

892489-52-0

AZD3988 Chemical Structure

892489-52-0

Chemical Structure

  • AZD3988
  • CAS No: 892489-52-0
    Formula: C23H22F2N4O4
    Molecular Weight: 456.44
  • IUPAC Name: 2-((1r,4r)-4-(4-(5-((3,4-difluorophenyl)amino)-1,3,4-oxadiazole-2-carboxamido)phenyl)cyclohexyl)acetic acid
  • InChIKey: NGEBYTLALFOQKI-HDJSIYSDSA-N
  • SMILES: O=C(NC1=CC=C(C=C1)[C@H](CC2)CC[C@@H]2CC(O)=O)C3=NN=C(NC4=CC=C(C(F)=C4)F)O3

Biological Activity: AZD3988 is an orally active diacylglycerol acyl transferase-1 (DGAT-1) inhibitor. AZD3988 has excellent DGAT-1 (human) potency with an IC50 value of 0. 6 nM. AZD3988 can be used for the research of metabolic diseases such as diabetes, obesity[1].

Cat. No. Product Name Purity Description
HY-50861 AZD3988 99.83% AZD3988 is an orally active diacylglycerol acyl transferase-1 (DGAT-1) inhibitor. AZD3988 has excellent DGAT-1 (human) potency with an IC50 value of 0. 6 nM. AZD3988 can be used for the research of metabolic diseases such as diabetes, obesity.

References

[1]. McCoull W, et al. Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3873-8. [Content Brief]

Keywords:

AZD3988