2. Stem Cell/Wnt
  3. Wnt
  4. 70222-95-6

70222-95-6

N,N-Dimethyldoxorubicin Chemical Structure

70222-95-6

Chemical Structure

  • N,N-Dimethyldoxorubicin
  • CAS No: 70222-95-6
    Formula: C29H33NO11
    Molecular Weight: 571.57
  • IUPAC Name: (8S,10S)-10-(((2R,4S,5S,6S)-4-(dimethylamino)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
  • InChIKey: DJEFXYVVRUAFEB-KYZOVJJKSA-N
  • SMILES: OC1=C2C(C(C3=C(OC)C=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N(C)C)=C1C[C@](O)(C4)C(CO)=O

Biological Activity: N,N-Dimethyldoxorubicin is a Doxorubicin (HY-15142A) analogue. N,N-Dimethyldoxorubicin shows cytotoxicity against a panel of tumor cell lines (IC50s < 0.3 μM)[1].

Cat. No. Product Name Purity Description
HY-154797 N,N-Dimethyldoxorubicin N,N-Dimethyldoxorubicin is a Doxorubicin (HY-15142A) analogue. N,N-Dimethyldoxorubicin shows cytotoxicity against a panel of tumor cell lines (IC50s < 0.3 μM).

References

[1]. Wander DPA, et al. Synthetic (N,N-Dimethyl)doxorubicin Glycosyl Diastereomers to Dissect Modes of Action of Anthracycline Anticancer Drugs. J Org Chem. 2021 Apr 16;86(8):5757-5770. [Content Brief]

Keywords:

N,N-Dimethyldoxorubicin