2. NF-κB Stem Cell/Wnt JAK/STAT Signaling Apoptosis
  3. IKK STAT Apoptosis
  4. 300839-31-0

300839-31-0

StA-IFN-1 Chemical Structure

300839-31-0

Chemical Structure

  • StA-IFN-1
  • CAS No: 300839-31-0
    Formula: C14H13N3O2
    Molecular Weight: 255.27
  • IUPAC Name: 4-(1-acetyl-1H-indol-3-yl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one
  • InChIKey: LWAAWXPHUVBIOH-UHFFFAOYSA-N
  • SMILES: O=C1NN=C(C)C1C2=CN(C(C)=O)C3=C2C=CC=C3

Biological Activity: StA-IFN-1 is an inhibitor for type I interferon (IFN), that inhibits the activation of IFNβ with an IC50 of 4.1 μM[1].

Cat. No. Product Name Purity Description
HY-126063 ICI-204448 free acid ICI-204448 free acid is a κ-opioid agonist with limited access to the CNS, ICI-204448 free acid can displace the binding of the kappa-opioid ligand 3H-bremazocine from guinea pig cerebellum membranes.

References

[1]. Gage ZO, et al., Identification of Novel Inhibitors of the Type I Interferon Induction Pathway Using Cell-Based High-Throughput Screening. J Biomol Screen. 2016 Oct;21(9):978-88. [Content Brief]

Keywords:

StA-IFN-1