99777-90-9

Chemical Structure

NF023
CAS No: 99777-90-9

Formula: C₃₅H₂₆N₄O₂₁S₆

Molecular Weight: 1030.99
InChIKey: JMONOAYAUIIKMS-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC(C(NC2=CC=C(S(=O)(O)=O)C3=CC(S(=O)(O)=O)=CC(S(=O)(O)=O)=C23)=O)=C1)NC4=CC=CC(C(NC5=CC=C(S(=O)(O)=O)C6=CC(S(=O)(O)=O)=CC(S(=O)(O)=O)=C56)=O)=C4

Biological Activity: NF023 is a compound that inhibits X-BIR1/TAB1 assembly activity. NF023 can affect cell survival signaling pathways by interfering with XIAP-mediated NF-κB activation. NF023 also shows potential as a selective P2X1 adenylate receptor antagonist. This compound has the potential to synergize with existing pro-apoptotic drugs and play an important role in cancer suppression^[1].

Cat. No.	Product Name	Purity	Description
HY-167704	NF023		NF023 is a compound that inhibits X-BIR1/TAB1 assembly activity. NF023 can affect cell survival signaling pathways by interfering with XIAP-mediated NF-κB activation. NF023 also shows potential as a selective P2X1 adenylate receptor antagonist. This compound has the potential to synergize with existing pro-apoptotic drugs and play an important role in cancer suppression.

References

[1]. NF023 binding to XIAP-BIR1: searching drugs for regulation of the NF-κB pathway

Keywords:

NF023

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