2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 3219-99-6

3219-99-6

6-epi Doxycycline Chemical Structure

3219-99-6

Chemical Structure

  • 6-epi Doxycycline
  • CAS No: 3219-99-6
    Formula: C22H24N2O8
    Molecular Weight: 444.43
  • IUPAC Name: (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
  • InChIKey: JBIWCJUYHHGXTC-IPJAVASBSA-N
  • SMILES: O[C@]12[C@]([C@H]([C@@]3([H])C(C(C4=C(O)C=CC=C4[C@H]3C)=O)=C2O)O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C)C

Biological Activity: 6-Epi-doxycycline is the C-6 epimer of Doxycycline (HY-N0565), formed as a degradation impurity through epimerization of Doxycycline under abnormal conditions (e.g., high temperature, pH changes, or humidity). 6-Epi-doxycycline is commonly used for the detection and analysis of impurity levels in pharmaceutical formulations[1].

Cat. No. Product Name Purity Description
HY-148124 6-epi Doxycycline 6-Epi-doxycycline is the C-6 epimer of Doxycycline (HY-N0565), formed as a degradation impurity through epimerization of Doxycycline under abnormal conditions (e.g., high temperature, pH changes, or humidity). 6-Epi-doxycycline is commonly used for the detection and analysis of impurity levels in pharmaceutical formulations.

References

[1]. Monser L, et al Rapid liquid chromatographic method for simultaneous determination of tetracyclines antibiotics and 6-epi-doxycycline in pharmaceutical products using porous graphitic carbon column. J Pharm Biomed Anal. 2000 Aug 15;23(2-3):353-62. [Content Brief]

Keywords:

6-epi Doxycycline