1. Cell Cycle/DNA Damage Metabolic Enzyme/Protease Immunology/Inflammation Anti-infection
  2. HSP Interleukin Related Enterovirus
  3. 544712-82-5

544712-82-5

Pochonin D Chemical Structure

544712-82-5

Chemical Structure

  • Pochonin D
  • Synonym(s): (+)-Pochonin D
  • CAS No: 544712-82-5
    Formula: C18H19ClO5
    Molecular Weight: 350.79
  • InChIKey: FJVQHTGEXYKKBS-CJRGTMQESA-N
  • SMILES: ClC1=C2C(C(O[C@@H](C/C=C/CC/C=C/C(C2)=O)C)=O)=C(C=C1O)O

Biological Activity: Pochonin D ((+)-Pochonin D) is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory activities. Pochonin D inhibits Hsp90, affecting the homeostasis, folding, and assembly processes of viral proteins, reducing the replication ability of the virus. Pochonin D reduces the infiltration of inflammatory cells and the secretion of inflammatory cytokines such as TNF-α and IL-1β, alleviating the inflammatory response. Pochonin D is promising for research of Human rhinoviruses (HRV) infections and cancers[1].

References

Keywords:

Pochonin D